Software developed in my lab
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GUST: Genes under Selection in Tumors Predicts oncogenes, tumor suppressor genes and passenger genes using somatic SNVs detected in a collection of tumors. It supports contextual classifications of genes for specific tissue types and cancer types. |
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Know-GRRF: Know–Guided Regularized Random Forests Incorporates prior knowledge from multiple domains to guide feature selection. It provides a general framework for all feature selection tasks. We demonstrate its power in biomarker discovery. |
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MAGOS: Model-based Adaptive Grouping of Subclones Decompose subclonal structure in tumors from bulk-sequencing data. It makes accurate and reproducible subclone identifications in samples sequenced at depth as low as 30x, thus suitable to analyzing whole-genome sequencing data. |
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TreeMap: A Nested Machine- and Statistical-Learning Approach to Discover Causal Variant Fine-map causal variants for eQTL and GWAS studies by considering hierarchical linkage structure among genetic variants. |
TreeGuidedLasso: An R implementation of the tree-guided group lasso algorithm |